Research conducted at the European Molecular Biology Laboratory has
suggested that microRNA (miRNA) - small nucleic acid sequences of
20-24 nucleotides that do not code for proteins - in fact play a
key role in gene expression.
Juvantia Pharma identifies small-molecule inhibitors of two forms
of the somatostatin receptor - subtypes 1 and 4 - with potential in
a wide range of disease indications.
Inamed has signed up Bayer BP for its computer-controlled AKITA
inhaler, designed to improve respiratory treatment by tailoring the
delivery of inhaled drugs.
Process manufacturing industries are not responding to a clear need
to improve the information flow between the different parts of
their businesses leading to costly plant shutdowns, says a new
survey commissioned by BASF IT Services.
Affymetrix releases into the public domain what it says is the
first significant SNP database that includes genotype data and
allele frequencies across the entire human genome.
General Electric is the company offering to buy Amersham of the UK,
it was confirmed today. The US group is offering £5.7 billion for
the life sciences group, and said it has no plans to hive off
Biosciences.
After Amersham confirmed yesterday that it had received a bid from
an unnamed suitor wishing to buy the entire company, its shares
rose more than 16 per cent; both J&J and Roche are in the
rumour mill.
DRI and Tecan UK forge an alliance to use the former's CST reagents
on Tecan's liquid-handling devices. The collaboration will provide
automated nucleic acid purification systems.
Scientists at Berlex Pharmaceuticals, the US subsidiary of
Germany's Schering, have identified a biologic marker for
Alzheimer's that could form the basis of a diagnostic test.
Axon has licensed rights to Cellectricon's electroporation
technology to enhance the performance of its Axoporator products,
used to deliver DNA and other large molecules into cells.
New microarray products covering the human genome have been
launched by MWG Biotech and Agilent Technologies, adding to the
choice of products available to researchers.
Amersham will no longer act as a distributor for Epoch Bioscience's
MGB Eclipse range of probe systems after failing to meet sales
targets, according to the latter company.
Thermo Electron has teamed up with IBM to launch an offensive on
the LIMS marketplace. The collaboration will focus on LIMS systems
based on IBM's eServer system hardware.
Epigenomics and the Wellcome Trust Sanger Institute are to press
ahead with the first phase of the Human Epigenome Project following
the successful completion of a pilot study funded by the European
Union.
French company genOway has become the first in the world to clone
rats, opening the way towards genetically-modified animals that can
be used as reliable, reproducible models of disease processes.
Cardinal Health is to acquire 100 per cent ownership of protein
production specialist Gala Biotech for $15.5 million (€13.2m)in a
move to bolster its drug development services business.
NextGen Sciences of the UK has launched two new technologies that
it maintains have the potential to revolutionise protein research
and accelerate drug discovery.
Serono has initiated Phase I clinical testing of TACI-Ig, a soluble
receptor-based drug that may have a role to play in the management
of autoimmune diseases.
CalbaTech has signed an agreement to acquire privately-held
Molecula Research Laboratories, a company developing gene silencing
technologies for gene and protein function studies.
BioFocus has entered into an agreement with Switzerland's Roche for
the design of a several custom kinase libraries for use in the
latter's drug discovery efforts.
Germany's Bayer has continued the revamp of its business units by
setting up its chemicals, technology services and healthcare
activities as three separate legal entities. The move follows the
carve-out of Bayer CropScience a...
Iceland's deCODE Genetics saw its US-listed shares rise more than
10 per cent yesterday after it reported the discovery of a gene
that appears to play a role in whether people are lean or fat.
Another drug targeting epidermal growth factor tyrosine kinase -
Roche's Tarceva, has failed to live up to early promise as a
treatment for lung cancer.
A consortium of companies and academic researchers has completed
the first phase of a mammoth screening programme designed to
discover a small-molecule drug candidate for smallpox.
Tepnel Life Sciences has trimmed its losses and boosted sales in
the year ended 30 June, helped by the sale last month of its first
robotic Nucleopure DNA purification systems.
Swedish company Perbio Science has agreed to a $714 million (€626m)
takeover by Fisher Scientific International of the USA, which says
that it sees the acquisition as a means of capitalising on the
strong growth of the life science...
The world market for toxicogenomics technologies is set to grow
strongly over the next five years, but needs the catalyst of
recognition by regulatory authorities.
Researchers from Icelandic genomics company deCODE Genetics have
discovered the first gene ever linked to ischaemic stroke, raising
the hope that new drugs to treat the condition may be developed.
Akubio bolsters its position in acoustic detection, which uses
sound to detect the interactions between molecules, by licensing a
complementary technology from GlaxoSmithKline.
GlaxoSmithKline has secured rights to a technology, developed in
partnership with US company Advaxis, could improve the
effectiveness of vaccine-based treatments for cancer.
Pall tells BIOPHEX/INTERPHEX conference that use of its
ultrafiltration technologies cuts both the time and cost of
conjugate vaccine production; greater adoption could increase the
availability of vaccines for diseases such as meningitis...
Researchers at Merck Research Laboratories have discovered a
small-molecule drug that blocks the activity of FtsZ, an emerging
therapeutic target for antibacterial agents.
